The first experience of injecting of bulking agents in mild stress incontinence in reproductive age womens


DOI: 10.29188/2222-8543-2020-12-2-158-163

Cukanov A.Yu., Mirzakadiev A.A., Dunkurs A.V.
№2 2020

Introduction. Stress urinary incontinence is one of the common forms of urinary incontinence in women. This disease occurs at all ages with a population incidence, according to various sources, of 29% to 75%. The traditional surgery of choice is the implantation of a free synthetic loop, which is accompanied by a number of complications. The injection of volume-forming substances is considered as an alternative for the treatment of stress urinary incontinence in elder patients, somatically burdened patients or if a patient refuses surgery. The aim of the study: to evaluate the efficacy and safety of injectable suburethral volume-forming substances in a mild stress urinary incontinence in women of reproductive age.

Materials and methods. The results of the volume-forming substances use in patients with stress urinary incontinence were studied. Patients were randomized to the main (n = 37) and control (n = 42) groups. In both groups, a series of exercises were taken to strengthen the pelvic floor muscles, patients from the main group were additionally injected suburethrally with a volume-forming substance. Control examinations were performed after three and six months.

Results. Local sensations after the injection of volume-forming substance were minimal, managed on their own. After 3 months in the main group, the proportion of patients with the achieved state of the continent was 91.9% versus 64.3% in the control group (p = 0.019), after 6 months, 97.3% and 78.5% (p = 0.027), respectively. Six months later, the posterior urethrovesical angle in patients in the main group decreased from 130.6 ° to 102.4 ° (p <0.05), in the control group this indicator did not change from the initial value. In the main group, bladder neck displacement decreased by 30.0% and 41.1% after 3 and 6 months, respectively (p <0.01, compared with the control). In the control group, the severity of urinary incontinence decreased by the third month and did not change further.

Conclusion. Injection of volume-forming substances in case of urinary incontinence with mild exertion in women of reproductive age is a less traumatic effective procedure and can be used as a first-line treatment with sufficient patient awareness

Conflict of interest. The authors declare no conflict of interest

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